Publications

Featured Publications

Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection. Cell Host & Microbe View

Pham, T. H., Brewer, S. M., Thurston, T., Massis, L. M., Honeycutt, J., Lugo, K., Jacobson, A. R., Vilches-Moure, J. G., Hamblin, M., Helaine, S., Monack, D. M.2019

Preview in Cell Host & Microbe

Single-cell profiling identifies ACE+ granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent Salmonella infection. Science Advances View

Pham, T. H.*, Xue, Y.*, Brewer, S. M., Bernstein, K. E., Quake, S. R., Monack, D. M. 2023; 9 (1): eadd4333

Turning foes into permissive hosts: manipulation of macrophage polarization by intracellular bacteria. Current opinion in immunology View

Pham, T. H., Monack, D. M. 2023; 84: 102367

S1P(1) receptor signaling overrides retention mediated by G alpha(i)-coupled receptors to promote T cell egress Immunity View

Pham, T. H., Okada, T., Matioubian, M., Lo, C. G., Cyster, J. G. 2008; 28 (1): 122-133

Preview in Immunity

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning JOURNAL OF EXPERIMENTAL MEDICINE View

Pham, T. H., Baluk, P., Xu, Y., Grigorova, I., Bankovich, A. J., Pappu, R., Coughlin, S. R., McDonald, D. M., Schwab, S. R., Cyster, J. G. 2010; 207 (1): 17-27

All Publications

  • Turning foes into permissive hosts: manipulation of macrophage polarization by intracellular bacteria. Current opinion in immunology Pham, T. H., Monack, D. M.2023; 84: 102367 More

  • Single-cell profiling identifies ACE+ granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent Salmonella infection. Science advances Pham, T. H., Xue, Y., Brewer, S. M., Bernstein, K. E., Quake, S. R., Monack, D. M.2023; 9 (1): eadd4333 More

  • Near-fatal Legionella pneumonia in a neonate linked to home humidifier by metagenomic next generation sequencing. Med (New York, N.Y.) West, P. T., Brooks, E. F., Costales, C., Moreno, A., Jensen, T. D., Budvytiene, I., Khan, A., Pham, T. H., Schwenk, H. T., Bhatt, A. S., Banaei, N. 2022 More

  • A Salmonella Typhi RNA thermosensor regulates virulence factors and innate immune evasion in response to host temperature. PLoS pathogens Brewer, S. M., Twittenhoff, C., Kortmann, J., Brubaker, S. W., Honeycutt, J., Massis, L. M., Pham, T. H., Narberhaus, F., Monack, D. M. 2021; 17 (3): e1009345 More

  • Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection. Cell host & microbe Pham, T. H., Brewer, S. M., Thurston, T., Massis, L. M., Honeycutt, J., Lugo, K., Jacobson, A. R., Vilches-Moure, J. G., Hamblin, M., Helaine, S., Monack, D. M. 2019 More

  • Salmonella Effector SteE Converts the Mammalian Serine/Threonine Kinase GSK3 into a Tyrosine Kinase to Direct Macrophage Polarization. Cell host & microbe Panagi, I., Jennings, E., Zeng, J., Gunster, R. A., Stones, C. D., Mak, H., Jin, E., Stapels, D. A., Subari, N. Z., Pham, T. H., Brewer, S. M., Ong, S. Y., Monack, D. M., Helaine, S., Thurston, T. L. 2019 More

  • A Gut Commensal-Produced Metabolite Mediates Colonization Resistance to Salmonella Infection. Cell host & microbe Jacobson, A., Lam, L., Rajendram, M., Tamburini, F., Honeycutt, J., Pham, T. H., Van Treuren, W., Pruss, K., Stabler, S. R., Lugo, K., Bouley, D. M., Vilches-Moure, J. G., Smith, M., Sonnenburg, J. L., Bhatt, A. S., Huang, K. C., Monack, D. 2018 More

  • Well-Appearing Newborn With a Vesiculobullous Rash at Birth. Pediatrics Stewart, S. E., Lin, J. L., Everhart, J. L., Pham, T. H., Marqueling, A. L., Rieger, K. E., Hilgenberg, S. L. 2018 More

  • Pseudogenization of the Secreted Effector Gene sseI Confers Rapid Systemic Dissemination of S. Typhimurium ST313 within Migratory Dendritic Cells. Cell host & microbe Carden, S. E., Walker, G. T., Honeycutt, J., Lugo, K., Pham, T. H., Jacobson, A., Bouley, D., Idoyaga, J., Tsolis, R. M., Monack, D. 2017; 21 (2): 182-194 More

  • DOCK8 is essential for T-cell survival and the maintenance of CD8(+) T-cell memory EUROPEAN JOURNAL OF IMMUNOLOGY Lambe, T., Crawford, G., Johnson, A. L., Crockford, T. L., Bouriez-Jones, T., Smyth, A. M., Pham, T. H., Zhang, Q., Freeman, A. F., Cyster, J. G., Su, H. C., Cornall, R. J. 2011; 41 (12): 3423-3435 More

  • GRK2-Dependent S1PR1 Desensitization Is Required for Lymphocytes to Overcome Their Attraction to Blood SCIENCE Arnon, T. I., Xu, Y., Lo, C., Pham, T. H., An, J., Coughlin, S., Dorn, G. W., Cyster, J. G. 2011; 333 (6051): 1898-1903 More

  • Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning JOURNAL OF EXPERIMENTAL MEDICINE Pham, T. H., Baluk, P., Xu, Y., Grigorova, I., Bankovich, A. J., Pappu, R., Coughlin, S. R., McDonald, D. M., Schwab, S. R., Cyster, J. G. 2010; 207 (1): 17-27 More

  • Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice JOURNAL OF CLINICAL INVESTIGATION Camerer, E., Regard, J. B., Cornelissen, I., Srinivasan, Y., Duong, D. N., Palmer, D., Pham, T. H., Wong, J. S., Pappu, R., Coughlin, S. R. 2009; 119 (7): 1871-1879 More

  • Cortical sinus probing, S1P(1)-dependent entry and flow-based capture of egressing T cells NATURE IMMUNOLOGY Grigorova, I. L., Schwab, S. R., Phan, T. G., Pham, T. H., Okada, T., Cyster, J. G. 2009; 10 (1): 58-65 More

  • S1P(1) receptor signaling overrides retention mediated by G alpha(i)-coupled receptors to promote T cell egress IMMUNITY Pham, T. H., Okada, T., Matioubian, M., Lo, C. G., Cyster, J. G. 2008; 28 (1): 122-133 More

  • Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infection NATURE GENETICS Desrosiers, M. P., Kielczewska, A., Loredo-Osti, J. C., Adam, S. G., Makrigiannis, A. P., Lemieux, S., Pham, T. H., Lodoen, M. B., Morgan, K., Lanier, L. L., Vidal, S. M. 2005; 37 (6): 593-599 More

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